Crystal Structure of 3-Amino-1,2,4-triazin-5(2H)-one

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Crystal structure of 3-amino-1,2,4-triazin-5(2H)-one.

because of various interesting biological activities.1 The tautomeric proton is highly effective at making strong intermolecular hydrogen binding with other heteroatoms of molecules involved with biological activity. The title compound 3-amino-1,2,4-triazin-5(2H)-one (6-azaisocytosine, Fig. 1), an isosteric isomer of isocytosine, can exist in several tautomeric forms, which have been discussed ...

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Crystal structure of 6-amino-3-ethyl-1,2,4-triazolo[3,4-f][1,2,4]triazin-8(7H)-one.

interpret the detailed mechanisms of reactions of tautomeric heterocycles properly. The correct dominant tautomeric structure also makes it possible to interpret the biological activity and functions of potential tautomeric heterocycles.1 Many of these aza/deaza analogues of purine and their nuclosides have drawn considerable interest in biological activity. Compound 6-amino-1,2,4-triazolo[3,4-...

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Crystal structure of 3-amino-2-propyl­quinazolin-4(3H)-one

In the title mol-ecule, C11H13N3O, the propyl group is almost perpendicular to the quinazolin-4(3H)-one mean plane, making a dihedral angle of 88.98 (9)°. In the crystal, mol-ecules related by an inversion centre are paired via π-π overlap, indicated by the short distances of 3.616 (5) and 3.619 (5) Å between the centroids of the aromatic rings of neighbouring mol-ecules. Inter-molecular N-H⋯N ...

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Synthesis and molecular structure of 6-amino-3-benzylmercapto-1,2,4-triazolo[3,4-f][1,2,4]triazin-8(7H)-one.

The title compound 6-amino-3-benzylmercapto-1,2,4-triazolo[3,4-f][1,2,4]-triazin-8(7H)-one (4), molecular formula C(11)H(10)N(6)OS, was obtained by the reaction of 3-amino-2-benzyl-6-hydrazino-1,2,4-triazin-5(2H)-one (3) with carbon disulfide in a water/pyridine mixture. Compound 4 can also be synthesized by reacting 6-amino-3(2H)mercapto-1,2,4-triazolo[3,4-f][1,2,4]triazin-8(7H)-one (7) with b...

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Crystal structure of 3-amino-2-ethyl-quinazolin-4(3H)-one.

The mol-ecule of the title compound, C10H11N3O, is planar, including the ethyl group, as indicated by the N-C-C-C torsion angle of 1.5 (2)°. In the crystal, inversion-related mol-ecules are stacked along the a axis. Mol-ecules are oriented head-to-tail and display π-π inter-actions with a centroid-to-centroid distance of 3.6664 (8) Å. N-H⋯O hydrogen bonds between mol-ecules generate a 'step' st...

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ژورنال

عنوان ژورنال: Analytical Sciences

سال: 2002

ISSN: 0910-6340,1348-2246

DOI: 10.2116/analsci.18.723